An autonomous entity is the experience of perceived contact with beings that appear to be sentient in their behaviour. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds.

Colour enhancement is a perceived intensification of the brightness and vividness of colours in the external environment. It is most commonly induced under the influence of mild dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.

Double vision is the experience of seeing duplicated vision, similar to when one crosses their eyes. This effect is most commonly induced under the influence of moderate dosages of depressant and dissociative compounds, such as alcohol, quetiapine, ketamine, and DXM.

An external hallucination is the perception of a visual hallucination that displays itself seamlessly into the external environment as if it were physically present. They are most commonly induced under the influence of heavy dosages of deliriant compounds.

Geometry is the experience of a person's field of vision becoming partially or completely encompassed by fast-moving, colourful, and extremely complex geometric patterns, form constants, shapes, fractals, and colours.

Increased pareidolia is an increase in a person's ability and tendency to recognise patterns (usually faces) within vague stimuli. It is most commonly induced under the influence of mild dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.

An internal hallucination is the perception of a visual hallucination that exclusively occurs within an imagined environment that can typically only be viewed with closed eyes, similar to those found within dreams. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.

Peripheral information misinterpretation is a fleeting experience of an object or detail within one's peripheral vision being interpreted and displayed incorrectly. It is most commonly induced under the influence of moderate dosages of deliriant compounds, such as DPH, datura, and benzydamine.

A perspective hallucination is an alteration of the perspective through which a given internal or external hallucination is seen through. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.

Pupil dilation can be described as the enlargement of the size of a person's pupils under normal lighting conditions. This is most commonly induced under the influence of moderate dosages of a wide variety of serotonergic compounds, such as psychedelics, dissociatives, deliriants, entactogens, various stimulants, and some antidepressants.

Settings, sceneries, and landscapes are the perceived environments in which the plot of an internal or external hallucination occurs. This effect is capable of manifesting in a seemingly infinite variety of potential places and settings. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.

Symmetrical texture repetition is the perception of textures becoming mirrored repeatedly over their own surface in an intricate and symmetrical fashion that is consistent across itself. It is most commonly induced under the influence of mild dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.

Tracers are the experience of visual trails of varying lengths and opacity being left behind moving objects. They are most commonly induced under the influence of mild dosages of psychedelic compounds.

Visual exposure to semantic concept network is the experience of percieving a seemingly infinite mass of complex interconnected geometric forms comprised entirely of innately understandable representations. These individual geometric representations are perceived to simultaneously convey every internally stored concept and memory contained within the mind.

Physical euphoria can be described as feelings of pleasure and comfort within and across one's body. This euphoria typically feels somewhat comparable to the endorphin rushes felt during states of excitement or love, the coziness of a comfortable bed, and the rush of an orgasm. It is most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as opioids, stimulants, psychedelics, and GABAergics.

An abnormal heartbeat is any of a group of conditions in which the electrical activity of the heart is irregular. During this state, the heartbeat may be too fast (over 100 beats per minute) or too slow (less than 60 beats per minute) and may be regular or irregular. An abnormal heartbeat is most commonly induced under the influence of moderate dosages of stimulant and depressant compounds, such as cocaine, methamphetamine, and GABAergics.

Appetite suppression can be described as the experience of a distinct decrease in a person's sense of hunger and appetite in a manner which can result in both a lesser desire to eat food and a decreased enjoyment of its taste. It is most commonly induced under the influence of moderate dosages of stimulant compounds, such as amphetamine, methylphenidate, nicotine, MDMA, and cocaine.

Bodily control enhancement can be described as feeling as if there has been a distinct increase in a person's ability to control their physical body with precision, balance, coordination, and dexterity. It is most commonly induced under the influence of moderate dosages of stimulating psychedelics, such as LSD, 2C-B, and DOC.

Brain zaps can be described as sharp electrical shock sensations which originate within the head or brain and sometimes extend throughout the body. They are most commonly induced under the influence of withdrawal, dose reduction, and discontinuation of antidepressant drugs, including selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) such as sertraline, paroxetine, and venlafaxine.

Bronchodilation can be described as the expansion of the bronchial air passages in the respiratory tract. A bronchodilator is a substance that dilates the bronchial tubes resulting in decreased resistance in the respiratory airway and increased airflow to the lungs.

Decreased libido can be described as a distinct decrease in feelings of sexual desire, the anticipation of sexual activity, and the likelihood that a person will view the context of a given situation as sexual in nature. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds, such as, opioids, antipsychotics and SSRI's, and dissociatives.

Dehydration can be described as an uncomfortably dry mouth and feelings of general thirstiness that results due to a lack of water intake. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds such as, stimulants, psychedelics, opioids, dissociatives, deliriants, cannabinoids, alcohol, and antipsychotics.

Difficulty urinating (also known as urinary retention) can be described as the experience of a decreased ability to pass urine. It is most commonly induced under the influence of heavy dosages of stimulant and opioid compounds, such as heroin, fentanyl, kratom, amphetamine, MDMA, and 4-FA.

Dry mouth can be described as having a dry-feeling mouth often accompanied by a difficulty swallowing. It is usually a direct result of dehydration but can be felt to occur regardless of the actual dryness of a person's mouth. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds, such as stimulants, psychedelics, opioids, antispychotics, deliriants, SSRI's, and cannabinoids.

Excessive yawning can be described as the experience of repeated, intensified, overly frequent, and spontaneous yawning despite a complete absence of genuine sedation or sleepiness. It is most commonly induced under the influence of moderate dosages of tryptamine psychedelic compounds, such as psilocybin, 4-AcO-DMT, 4-HO-MET, and ayahuasca.

A headache can be described as a pain anywhere in the region of the head or neck. It can be a symptom of a number of different conditions. They are most commonly induced under the influence of heavy dosages of stimulating compounds, such as traditional stimulants, certain psychedelics, and certain dissociatives.

Increased blood pressure can be described as a condition in which the pressure in the systemic arteries is elevated to abnormal levels. It is most commonly induced under the influence of heavy dosages of deliriants and vasoconstricting compounds, such as traditional stimulants and stimulating psychedelics.

Increased bodily temperature or pyrexia can be described as having a body temperature which is above normal baseline. It is most commonly induced under the influence of heavy dosages of stimulant compounds which affect serotonin and 5-HT receptors, dopamine and D receptors and norepinephrine.

Increased heart rate or tachycardia is described as a heart rate that is faster than the normal heart rate at rest. It is most commonly induced under the influence of heavy dosages of stimulating compounds, such as traditional stimulants, certain psychedelics, and certain dissociatives.

Increased perspiration, or hyperhidrosis, can be described as a condition characterized by increased sweat which is in excess of that required for the regulation of body temperature. It is most commonly induced under the influence of stimulants, psychedelics, and benzodiapine or alcohol withdrawals.

Nausea can be described as a sensation of unease and discomfort in the upper stomach combined with an involuntary urge to vomit. It is most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as psychedelics, opioids, GABAergics, deliriants, dissociatives, and stimulants.

Orgasm suppression (formally known as anorgasmia) can be described as a difficulty or complete inability to achieve orgasm despite adequate sexual stimulation. This effect commonly occurs on opioids and dissociatives which have been reported to decrease one's ability to feel sexual pleasure, which may be attributed to their tactile suppressing effects or through some other biological mechanism. It is also a well-known side effect of selective serotonin reuptake inhibitors (SSRIs).

Pain relief can be described as an effect which suppresses negative sensations such as aches and pains. It is most commonly induced under the influence of moderate dosages of a very wide variety of compounds, such as opioids, GABAergics, GABApentinoids, cannabinoids, dissociatives, muscle relaxants, and NSAID's.

An epileptic seizure (colloquially a fit) can be described as a brief episode of signs and/or symptoms which are due to abnormal, excessive, or synchronous neuronal activity in the brain. They are most commonly induced under the influence of withdrawals from prolonged chronic benzodiazepine or alcohol usage.

Stamina enhancement can be described as an increased ability to engage in physically and mentally taxing activities without the development of fatigue. It most commonly occurs under the influence of stimulants such as amphetamine and specific psychedelics such as LSD.

Stimulation can be described as an increase in a person's physical energy levels. It is most commonly induced under the influence of stimulant compounds, such as amphetamine, MDMA, and cocaine.

Teeth grinding (also known as bruxism, jaw clenching, and gurning) can be described as a compulsive and often uncontrollable urge to grind one's teeth. It is most commonly induced under the influence of common dosages of stimulant compounds, such as methamphetamine, MDMA, methylphenidate, and cocaine. However, it can also occur under the influence of certain stimulating psychedelics such as 2C-E, DOC, and AMT.

Temperature regulation suppression can be defined as an inability to maintain a normal temperature. It is most commonly induced under the influence of heavy dosages of stimulating psychedelic compounds, such as LSD, 2C-B, and AMT.

Temporary erectile dysfunction can be described as a difficulty in achieving and maintaining an adequately erect penis for the purpose of sexual intercourse. It is most commonly induced under the influence of heavy dosages of stimulating compounds, such as traditional stimulants and certain psychedelics. However, it can also occur under the influence of opioids, dissociatives, GABAergics, and deliriants.

Vasoconstriction can be described as a narrowing of the veins and blood vessels which results from a contraction of their muscular wall. It is most commonly induced under the influence of moderate dosages of stimulating psychedelic compounds, such as LSD, 2C-E, and DOC.

Vibrating vision, also known as nystagmus, is the experience of constant, rapid involuntary eye movements in which the eyes shift from left to right in such quick succession that the person's vision begins to vibrate and blur. It is most commonly induced under the influence of heavy dosages of stimulant compounds, such as MDMA, amphetamine, and 4-FA.

Scenarios and plots are the situations, stories, and events that occur within both external and internal hallucinations. They are most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and deliriants.

An auditory distortion is the experience of perceived alterations in how audible noises present and structure themselves. They are most commonly induced under the influence of hallucinogenic compounds.

An auditory enhancement is the experience of an increase or improvement of the acuteness and clarity of sound. They are most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.

An auditory hallucination is the experience of hearing spontaneous and imaginary noises. They are most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, deliriants, and dissociatives.

Tinnitus is the experience of a sound which is usually described as a ringing, humming, buzzing, roaring, hissing, or clicking that occurs when no corresponding external sound is present. It can occur under the influence of a wide variety of compounds

Muscle twitching can be described as the sensation of small and localised tremblings of muscle groups. These vibrations are often powerful enough to be visibly seen through the skin. It is most commonly induced under the influence of moderate dosages of stimulating psychedelic compounds such as LSD, 2C-E, DOC, and AMT.

Spontaneous tactile sensations are the experience of sensations across the body occurring without any obvious or immediate physical trigger. This results in feelings of seemingly random yet distinct tingling sensations that occur across the skin and within the body. Depending on the psychoactive substance consumed, these vary greatly in their styles of sensation.

Tactile enhancement is an overall increase in both the intensity of a person's sense of touch and their awareness of the physical sensations across their body. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.

Amnesia is a global impairment in the ability to acquire new memories regardless of sensory modality, and a loss of some memories, especially recent ones, from the period before amnesia began. It is most commonly induced under the influence of heavy dosages of GABAergic depressants, such as alcohol, benzodiazepines, GHB, and zolpidem.

Anxiety is medically recognized as the experience of negative feelings of apprehension, worry, and general unease. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as cannabinoids, psychedelics, dissociatives, and deliriants

Anxiety suppression (also known as anxiolysis or minimal sedation) is medically recognized as a partial to complete suppression of a person’s ability to feel anxiety, general unease, and negative feelings of both psychological and physiological tension. It is most commonly induced under the influence of moderate dosages of anxiolytic compounds which primarily include GABAergic depressants, such as benzodiazepines, alcohol, GHB, and gabapentinoids.

Cognitive euphoria (semantically the opposite of cognitive dysphoria) is medically recognized as a cognitive and emotional state in which a person experiences intense feelings of well-being, elation, happiness, excitement, and joy. It is most commonly induced under the influence of moderate dosages of opioids, entactogens, stimulants, and GABAergic depressants. However, it can also occur to a lesser extent under the influence of hallucinogenic compounds such as psychedelics, dissociatives, and cannabinoids.

Cognitive fatigue (also called exhaustion, tiredness, lethargy, languidness, languor, lassitude, and listlessness) is medically recognized as a state usually associated with a weakening or depletion of one's mental resources. It is most commonly induced under the influence of moderate dosages of antipsychotic compounds, such as quetiapine, haloperidol, and risperidone.

Compulsive redosing is the experience of a powerful and difficult to resist urge to continuously redose a psychoactive substance in an effort to increase or maintain the subjective effects which it induces. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds, such as opioids, stimulants, GABAergics, and entactogens.

Confusion is an impairment of abstract thinking demonstrated by an inability to think with one’s customary clarity and coherence. It is most commonly induced under the influence of heavy dosages of hallucinogenic compounds, such as psychedelics, dissociatives, synthetic cannabinoids, and deliriants.

Creativity enhancement is a perceived increase in one's capability to imagine new ideas, create art, or think about existing concepts in a novel manner. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.

Delirium (also known as acute confusion) is medically recognized as a physiological disturbance of awareness that is accompanied by a change in baseline cognition which cannot be better explained by a preexisting or evolving neurocognitive disorder. The disturbance in awareness is manifested by a reduced ability to direct, focus, sustain, and shift attention and the accompanying cognitive change in at least one other area may include memory and learning (particularly recent memory), disorientation (particularly to time and place), alteration in language, or perceptual distortions or a perceptual-motor disturbance. It is most commonly induced under the influence of heavy dosages of deliriant compounds, such as DPH, datura, and benzydamine.

Depression medically encompasses a large variety of different mood disorders whose common features are a sad, empty, or irritable mood co-occurring with bodily and cognitive changes that significantly disrupt an individual's ability to function. Within the context of psychoactive substance usage, depressivity is often accompanied by other coinciding effects such as anxiety, irritability and dysphoria.

Depression reduction is the experience of minimizing the symptoms associated with depression and low mood states. It most commonly occurs at varying levels of efficacy under the influence of a range of different substances, primarily psychedelics in combination with psychotherapy, or dissociatives.

Derealization or derealisation (sometimes abbreviated as DR) is the experience of feeling detached from, and as if one is an outside observer of, one's surroundings (e.g., individuals or objects are experienced as unreal, dreamlike, foggy, lifeless, or visually distorted). It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.

Disinhibition is medically recognized as an orientation towards immediate gratification, leading to impulsive behavior driven by current thoughts, feelings, and external stimuli, without regard for past learning or consideration of future consequences. It is most commonly induced under the influence of moderate dosages of GABAergic depressants, such as alcohol, benzodiazepines, phenibut, and GHB.

Dream potentiation is an effect that increases the subjective intensity, vividness, and frequency of sleeping dream states. It is most commonly induced under the influence of moderate dosages of oneirogenic compounds, a class of hallucinogen that is used to specifically potentiate dreams when taken before sleep.

Dream suppression is a decrease in the vividness, intensity, frequency, and recollection of a person's dreams. It is most commonly induced under the influence of moderate dosages of cannabinoids and most types of antidepressants.

Ego inflation is an effect that magnifies and enhances one's own ego and self-regard, resulting in the person feeling an increased sense of confidence, superiority, and general arrogance. It is most commonly induced under the influence of moderate dosages of stimulant compounds, particularly dopaminergic stimulants, such as methamphetamine and cocaine.

Emotion intensification is an increase in a person's current emotional state beyond normal levels of intensity. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.

Empathy, affection, and sociability enhancement is the experience of a mind state that is dominated by intense feelings of compassion, talkativeness, and happiness. It is most commonly induced under the influence of moderate dosages of entactogenic compounds, such as MDMA, 4-FA, and 2C-B.

Existential self-realization can be described as a sudden realization, revelation, or reaffirmation of a person's existence within this universe. Existential self-realization is most commonly induced under the influence of moderate dosages of psychedelic and dissociative compounds such as ketamine, LSD, 4-AcO-DMT, and DCK.

Focus enhancement is the experience of an increased ability to selectively concentrate on an aspect of the environment while ignoring other things. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as amphetamine, methylphenidate, modafinil, and caffeine

Immersion enhancement is an effect that results in a pronounced increase in one's tendency to become fully captivated and engrossed by external stimuli, such as film, TV shows, video games, and various other forms of media. It is most commonly induced under the influence of moderate dosages of dissociative compounds, such as ketamine, PCP, and DXM.

Increased music appreciation is a general sense of an increased enjoyment of music. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and cannabinoids

Irritability is medically recognized as the pervasive and sustained emotional state of being easily annoyed and provoked to anger. It is most commonly induced during the after effects of heavy dosages of stimulant compounds, such as cocaine, methamphetamine, and methylphenidate.

Mindfulness is the self-regulation of attention so that focus is directed towards immediate experience alongside of an orientation characterized by acceptance and a lack of judgement. It can occur under the influence of substances but is also practiced during meditation.

Motivation enhancement is an increased desire to perform tasks and accomplish goals in a productive manner. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as amphetamine, methylphenidate, nicotine, and modafinil.

Motivation suppression (also known as avolition or amotivation) is a decreased desire to initiate or persist in goal-directed behavior. It is most commonly induced under the influence of an acute dosage of an antipsychotic compound, such as quetiapine, haloperidol, and risperidone. However, it is worth noting that chronic treatment with any dose of antipsychotic medication does not cause this effect.

Rejuvenation can be described as feelings of mild to extreme cognitive refreshment which are felt during the afterglow of certain compounds. It is most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics and dissociatives.

Suicidal ideation can be described as the experience of compulsive suicidal thoughts and a general desire to end one's own life. It is most commonly induced under the influence of moderate dosages of various antidepressants of the selective serotonin reuptake inhibitor class.

Thought acceleration (also known as racing thoughts) is the experience of thought processes being sped up significantly in comparison to that of everyday sobriety. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as amphetamine, methylphenidate, modafinil, and MDMA.

Thought deceleration is the process of thought being slowed down significantly in comparison to that of normal sobriety. It is most commonly induced under the influence of heavy dosages of depressant compounds, such as GABAergics, antipsychotics, and opioids.

Thought disorganization is a state in which one's ability to analyze and categorize conceptual information using a systematic and logical thought process is considerably decreased. It is most commonly induced under the influence of heavy dosages of hallucinogenic and depressant compounds, such as dissociatives, psychedelics, cannabinoids, and GABAergics.

Time distortion is an effect that makes the passage of time feel wildly altered and difficult to keep track of. is most commonly induced under the influence of strong dosages of hallucinogenic compounds, such as psychedelics, dissociatives, and cannabinoids.

Unity and interconnectedness refers to a feeling in which one's sense of self becomes temporarily expanded to include one or more concepts or systems that would not typically be included within one’s sense of individual identity. It most commonly occurs under the influence of psychedelic and dissociative compounds, such as LSD, DMT, ayahuasca, mescaline, and ketamine.

Wakefulness is an increased ability to stay conscious without feeling sleepy combined with a decreased need to sleep. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds such as stimulants, nootropics, and psychedelics.