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Bupropion
Also known as wellbutrin, zyban, amfebutamone
Bupropion
wellbutrin · zyban · amfebutamone
Overview
DescriptionTripSit
A frequently prescribed atypical antidepressant. Occasionally prescribed as an aid to smoking cessation. May lower seizure threshold in predisposed individuals. Poorly understood mechanism of action, probably an NDRI. Avoid combination with other drugs.
Sources & licencesTripSit·PubChem chemical identifiers
TripSit material is used non-commercially with attribution and a link to the source. Where combination information is shown, it is a quick reference and should be checked with further individual research.
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The SMILES and basic chemical identifiers are resolved from the linked PubChem record. Fracton renders the molecule locally as inline SVG.
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Chemical structure
Rendered locally from the bundled SMILES string.
Formula C13H18ClNO
Mass 239.74 g/mol
Show SMILES
CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)CTags1 tag
Dose
No dose chart available.
Safety
PrecautionsTripSit
Bupropion lowers the seizure threshold in a dose-dependent manner. Seizure risk increases significantly at total daily doses above 450 mg, with immediate-release formulations, rapid dose escalation, or when tablets are crushed or altered. Risk is further increased when combined with other substances that lower the seizure threshold, including CNS stimulants, alcohol (especially during withdrawal or binge use), theophylline, systemic corticosteroids, and certain antidepressants.
Effects
Effects
No effects are listed for this substance.
Timing
Timing chartTripSit
Only onset and total duration are available for this route, so an intensity curve would be misleading.
Onset15-90 minutes
Timing breakdownTripSit
Limited timing
Onset15-90 minutes
Detailed phase timing is not available from this source.
After effects1-6 hours
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