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5-Hydroxytryptophan
Also known as 5-htp, oxitriptan, cincofarm, levothym, levotonine, oxyfan, telesol, tript-oh, triptum
5-Hydroxytryptophan
5-HTP · Oxitriptan · Cincofarm · Levothym
Overview
The precursor to serotonin. In some countries it is sold OTC as a supplement for mood stabilisation and insomnia. It is frequently used as a recovery supplement following the use of MDMA/any other drug that depletes serotonin. It is not recommended to mix this drug with other serotonin releasers.
Sources & licencesPsychonautWiki·TripSit·PubChem chemical identifiers
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C1=CC2=C(C=C1O)C(=CN2)CC(C(=O)O)NTags3 tags
Dose
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Do not take this while on a serotonergic drug. It is recommended to wait at least 24 hours after taking MDMA (/similar) due to the concern of serotonin syndrome.
Safety
Anything which releases serotonin, such as MDMA and DXM.
EffectsPsychonautWikiEffectIndex
Visual
4Colour enhancement
Colour enhancement is a perceived intensification of the brightness and vividness of colours in the external environment. It is most commonly induced under the influence of mild dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Depth perception distortions
Depth perception distortions are alterations in how a person perceives the distance of various objects within their visual field. They are most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Drifting
Drifting is the experience of the texture, shape, and general structure of objects and scenery appearing progressively warped, melted, and morphed across themselves. It is most commonly induced under the influence of moderate dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline.
Open full explainer on EffectIndex↗Tracers
Tracers are the experience of visual trails of varying lengths and opacity being left behind moving objects. They are most commonly induced under the influence of mild dosages of psychedelic compounds.
Open full explainer on EffectIndex↗Physical & bodily
17Abnormal heartbeat
An abnormal heartbeat is any of a group of conditions in which the electrical activity of the heart is irregular. During this state, the heartbeat may be too fast (over 100 beats per minute) or too slow (less than 60 beats per minute) and may be regular or irregular. An abnormal heartbeat is most commonly induced under the influence of moderate dosages of stimulant and depressant compounds, such as cocaine, methamphetamine, and GABAergics.
Open full explainer on EffectIndex↗Appetite suppression
Appetite suppression can be described as the experience of a distinct decrease in a person's sense of hunger and appetite in a manner which can result in both a lesser desire to eat food and a decreased enjoyment of its taste. It is most commonly induced under the influence of moderate dosages of stimulant compounds, such as amphetamine, methylphenidate, nicotine, MDMA, and cocaine.
Open full explainer on EffectIndex↗Bodily control enhancement
Bodily control enhancement can be described as feeling as if there has been a distinct increase in a person's ability to control their physical body with precision, balance, coordination, and dexterity. It is most commonly induced under the influence of moderate dosages of stimulating psychedelics, such as LSD, 2C-B, and DOC.
Open full explainer on EffectIndex↗Diarrhea
Diarrhea or diarrhoea is the condition of having at least three loose or liquid bowel movements each day. It is most commonly induced under the influence of heavy dosages of certain psychedelic compounds, such as ayahuasca, mescaline, and psilocybin mushrooms.
Open full explainer on EffectIndex↗Dizziness
Dizziness can be described as the perception of a spinning or swaying motion which typically causes a difficulty in standing or walking. It is most commonly induced under the influence of heavy dosages of GABAergic depressant compounds, such as benzodiazepines, alcohol, and GHB.
Open full explainer on EffectIndex↗Headache
A headache can be described as a pain anywhere in the region of the head or neck. It can be a symptom of a number of different conditions. They are most commonly induced under the influence of heavy dosages of stimulating compounds, such as traditional stimulants, certain psychedelics, and certain dissociatives.
Open full explainer on EffectIndex↗Heartburn
PsychonautWiki lists Heartburn as a reported subjective effect for 5-Hydroxytryptophan. A concise EffectIndex summary is not available for this entry.
View on PsychonautWiki↗Increased blood pressure
Increased blood pressure can be described as a condition in which the pressure in the systemic arteries is elevated to abnormal levels. It is most commonly induced under the influence of heavy dosages of deliriants and vasoconstricting compounds, such as traditional stimulants and stimulating psychedelics.
Open full explainer on EffectIndex↗Increased heart rate
Increased heart rate or tachycardia is described as a heart rate that is faster than the normal heart rate at rest. It is most commonly induced under the influence of heavy dosages of stimulating compounds, such as traditional stimulants, certain psychedelics, and certain dissociatives.
Open full explainer on EffectIndex↗Nausea
Nausea can be described as a sensation of unease and discomfort in the upper stomach combined with an involuntary urge to vomit. It is most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as psychedelics, opioids, GABAergics, deliriants, dissociatives, and stimulants.
Open full explainer on EffectIndex↗Physical fatigue
Physical fatigue can be described as a general feeling of bodily exhaustion. It is most commonly induced under the influence of moderate dosages of antipsychotic compounds, such as quetiapine, haloperidol, and risperidone. However, it can also occur during the withdrawal symptoms of many depressants, and during the offset of many stimulants.
Open full explainer on EffectIndex↗Sedation
Sedation can be described as a decrease in a person's physical energy levels which are interpreted as discouraging when it comes to wakefulness, movement, performing tasks, talkativeness, and general exercise. It is most commonly induced under the influence of moderate dosages of depressant compounds, such as opioids, GABAergics, and antipsychotics.
Open full explainer on EffectIndex↗Sleep paralysis
PsychonautWiki lists Sleep paralysis as a reported subjective effect for 5-Hydroxytryptophan. A concise EffectIndex summary is not available for this entry.
View on PsychonautWiki↗Stimulation
Stimulation can be described as an increase in a person's physical energy levels. It is most commonly induced under the influence of stimulant compounds, such as amphetamine, MDMA, and cocaine.
Open full explainer on EffectIndex↗Stomach bloating
Stomach bloating can be described as an uncomfortable physical side effect which results in one's stomach becoming temporarily bloated and expanded in a manner which looks somewhat similar to pregnancy. It is most commonly induced under the influence of heavy dosages of psychedelic compounds, such as LSD, psilocybin, and mescaline. However, it can also occur under the influence of stimulants, opioids, and depressants.
Open full explainer on EffectIndex↗Stomach cramp
A stomach cramp can be described as an intense feeling of sudden pain or discomfort which occurs within the stomach. They are most commonly induced under the influence of heavy dosages of a wide variety of compounds, such as psychedelics, opioids, GABAergics, and deliriants.
Open full explainer on EffectIndex↗Teeth grinding
Teeth grinding (also known as bruxism, jaw clenching, and gurning) can be described as a compulsive and often uncontrollable urge to grind one's teeth. It is most commonly induced under the influence of common dosages of stimulant compounds, such as methamphetamine, MDMA, methylphenidate, and cocaine. However, it can also occur under the influence of certain stimulating psychedelics such as 2C-E, DOC, and AMT.
Open full explainer on EffectIndex↗Auditory
2Auditory hallucination
An auditory hallucination is the experience of hearing spontaneous and imaginary noises. They are most commonly induced under the influence of moderate dosages of hallucinogenic compounds, such as psychedelics, deliriants, and dissociatives.
Open full explainer on EffectIndex↗Tinnitus
Tinnitus is the experience of a sound which is usually described as a ringing, humming, buzzing, roaring, hissing, or clicking that occurs when no corresponding external sound is present. It can occur under the influence of a wide variety of compounds
Open full explainer on EffectIndex↗Cognitive
9Anxiety suppression
Anxiety suppression (also known as anxiolysis or minimal sedation) is medically recognized as a partial to complete suppression of a person’s ability to feel anxiety, general unease, and negative feelings of both psychological and physiological tension. It is most commonly induced under the influence of moderate dosages of anxiolytic compounds which primarily include GABAergic depressants, such as benzodiazepines, alcohol, GHB, and gabapentinoids.
Open full explainer on EffectIndex↗Cognitive euphoria
Cognitive euphoria (semantically the opposite of cognitive dysphoria) is medically recognized as a cognitive and emotional state in which a person experiences intense feelings of well-being, elation, happiness, excitement, and joy. It is most commonly induced under the influence of moderate dosages of opioids, entactogens, stimulants, and GABAergic depressants. However, it can also occur to a lesser extent under the influence of hallucinogenic compounds such as psychedelics, dissociatives, and cannabinoids.
Open full explainer on EffectIndex↗Dream potentiation
Dream potentiation is an effect that increases the subjective intensity, vividness, and frequency of sleeping dream states. It is most commonly induced under the influence of moderate dosages of oneirogenic compounds, a class of hallucinogen that is used to specifically potentiate dreams when taken before sleep.
Open full explainer on EffectIndex↗Memory enhancement
Memory enhancement is an improvement in a person's ability to recall or retain memories. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as methylphenidate, caffeine, Noopept, nicotine, and modafinil.
Open full explainer on EffectIndex↗Mindfulness
Mindfulness is the self-regulation of attention so that focus is directed towards immediate experience alongside of an orientation characterized by acceptance and a lack of judgement. It can occur under the influence of substances but is also practiced during meditation.
Open full explainer on EffectIndex↗Motivation enhancement
Motivation enhancement is an increased desire to perform tasks and accomplish goals in a productive manner. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as amphetamine, methylphenidate, nicotine, and modafinil.
Open full explainer on EffectIndex↗Sleepiness
Sleepiness (also known as drowsiness) is medically recognized as a state of near-sleep, or a strong desire for sleep without feeling a decrease in one's physical energy levels. This state is independent of a circadian rhythm; so, unlike sedation, this effect does not necessarily decrease physical energy levels but instead decreases wakefulness. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds such as cannabinoids, GABAergic depressants, opioids, antipsychotics, some antihistamines, and certain psychedelics.
Open full explainer on EffectIndex↗Thought acceleration
Thought acceleration (also known as racing thoughts) is the experience of thought processes being sped up significantly in comparison to that of everyday sobriety. It is most commonly induced under the influence of moderate dosages of stimulant and nootropic compounds, such as amphetamine, methylphenidate, modafinil, and MDMA.
Open full explainer on EffectIndex↗Thought deceleration
Thought deceleration is the process of thought being slowed down significantly in comparison to that of normal sobriety. It is most commonly induced under the influence of heavy dosages of depressant compounds, such as GABAergics, antipsychotics, and opioids.
Open full explainer on EffectIndex↗No effects match that search.
Timing
Only onset and total duration are available for this route, so an intensity curve would be misleading.
Detailed phase timing is not available from this source.
Testing
No testing reference is available for this substance.
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